MANF Mesencephalic Astrocyte-Derived Neurotrophic Factor Mouse Recombinant Protein

Supplier: Boster
Reference: PROTQ9CXI5
Name: MANF Mesencephalic Astrocyte-Derived Neurotrophic Factor Mouse Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET; Manf; Armet
Unit: 5ug 20ug 1mg
Price: Consultar
Format: Sterile Filtered White lyophilized (freeze-dried) powder.
Reactivity: Mouse
Description: MANF Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 158 amino acids and having a molecular mass of 18.2kDa.
Function: Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents
Cell localization: Secreted
Purification: Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Storage conditions: Lyophilized MANF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MANF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a c
Aa sequence: LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIEEELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDNQ IDLSTVDLKK LRVKELKKIL DDWGEMCKGC AEKSDYIRKI NELMPKYAPK AASARTDL