CENPA Centromere Protein A Human Recombinant Protein

Supplier: Boster
Reference: PROTP49450
Name: CENPA Centromere Protein A Human Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: Histone H3-like centromeric protein A; Centromere protein A; CENP-A; Centromere autoantigen A; CENPA
Unit: 5ug 20ug 1mg
Price: Consultar
Format: Sterile Filtered liquid formulation.
Reactivity: Human
Application: WB
Description: CENPA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 17,015 Dalton. CENPA is expressed with a -6x His tag and purified by proprietary chromatographic techniques. Applications: Western blot with monoclonal
Function: Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome se
Cell localization: Nucleus. Chromosome, centromere, kinetochore. Localizes exclusively in the kinetochore domain of centromeres. Occupies a compact domain at the inner kinetochore plate stretching across 2 thirds of the length of the constriction but encompassing only one
Purification: Greater than 90% as determined by SDS-PAGE.
Storage conditions: Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.