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IDE Insulin-Degrading Enzyme Human Recombinant Protein

Supplier: Boster
Reference: PROTP14735
Name: IDE Insulin-Degrading Enzyme Human Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: Insulin-Degrading Enzyme; Abeta-Degrading Protease; Insulin Protease; EC 3.4.24.56; Insulinase; INSULYSIN; Insulysin; EC 3.4.24; IDE
Unit: 2ug 10ug 1mg
Price: Consultar
Format: Filtered colorless solution.
Reactivity: Human
Description: IDE Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (Met1-Leu1019) containing 1026 amino acids including a 7 aa His tag at C-terminus. The total calculated molecular mass is 119kDa.
Function: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clear
Cell localization: Cytoplasm. Cell membrane. Secreted
Purification: Greater than 95.0% as determined by SDS-PAGE.
Storage conditions: Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Aa sequence: MRYRLAWLLH PALPSTFRSV LGARLPPPER LCGFQKKTYS KMNNPAIKRI GNHITKSPED KREYRGLELA NGIKVLLISD PTTDKSSAAL DVHIGSLSDP PNIAGLSHFC EHMLFLGTKK YPKENEYSQF LSEHAGSSNA FTSGEHTNYY FDVSHEHLEG ALDRFAQFFL CPLFDESCKD REVNAVDSEH EKNVMNDAWR LFQLEKATGN PKHPFSKFGT GNKYTLETRP NQ
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