TNFSF12 TNF Ligand Superfamily Member 12 Human Recombinant Protein

Supplier: Boster
Reference: PROTO43508
Name: TNFSF12 TNF Ligand Superfamily Member 12 Human Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: TWEAK; TNF-related weak inducer of apoptosis; TNFSF12; DR3LG; Apo3-Ligand; APO3L; TNFRSF12A; Tumor necrosis factor ligand superfamily member 12; MGC20669; MGC129581
Unit: 5ug 25ug 1mg
Price: Consultar
Format: Filtered White lyophilized (freeze-dried) powder.
Reactivity: Human
Description: TNFSF12 Human Recombinant (94-249 a.a.) produced in E. coli is a single, non-glycosylated, polypeptide chain containing 156 amino acids and having a total molecular mass of 18kDa. The TNFSF12 is fused with an 8 amino acids his tag at N-terminal (M-HHHHHH-
Function: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promot
Cell localization: Cell membrane
Purification: Greater than 95% as determined by SDS-PAGE.
Storage conditions: Lyophilized TNFSF12 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TWEAK should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add
Aa sequence: SA PKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH