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MTDH Metadherin Human Recombinant Protein

Supplier: Boster
Reference: PROTQ86UE4
Name: MTDH Metadherin Human Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: Metadherin; Lysine-Rich CEACAM1 Co-Isolated Protein; Astrocyte Elevated Gene-1 Protein; Metastasis Adhesion Protein; Astrocyte Elevated Gene 1; 3D3/LYRIC; AEG-1; LYRIC; AEG1; LYRIC/3D3; 3D3; MTDH
Unit: 2ug 10ug 1mg
Price: Consultar
Format: Filtered White lyophilized (freeze-dried) powder.
Reactivity: Human
Description: Metadherin Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (Val271-Asn456) containing 196 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 21.5kDa.
Function: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF- kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in
Cell localization: Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane
Purification: Greater than 90.0% as determined by SDS-PAGE.
Storage conditions: Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Aa sequence: VSSGLNENLT VNGGGWNEKS VKLSSQISAG EEKWNSVSPA SAGKRKAEPS AWSQDTGDAN TNGKDWGRSW SDRSIFSGIG STAEPVSQST TSDYQWDVSR NQPYIDDEWS GLNGLSSADP NSDWNAPAEE WGNWVDEERA SLLKSQEPIP DDQKVSDDDK EKGEGALPTG KSKKKKKKKK KQGEDN
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