| Supplier: | Boster |
|---|---|
| Reference: | M00016-1 |
| Name: | Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267 |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Monoclonal Antibodies |
| Research Area: | Cancer,Cancer Susceptibility,Cell Biology,Cell Cycle,Cell Cycle Inhibitors,Epigenetics and Nuclear Signaling,Oncoproteins/Suppressors,p53 Pathway,Transcription,Tumor Suppressors |
| Aditional Names: | Cyclin-dependent kinase inhibitor 2A;Cyclin-dependent kinase 4 inhibitor A;CDK4I;Multiple tumor suppressor 1;MTS-1;p16-INK4a;p16-INK4;p16INK4A;CDKN2A;CDKN2, MTS1; |
| Unit: | 100uL |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide corresponding to the C-terminus of human |
| Host: | Rabbit |
| Reactivity: | Human |
| Cross Reactivity: | This antibody reacts to human p16INK4a (Cyclin-dependent kinase inhibitor 2A). |
| Application: | IHC,WB |
| Description: | Boster Bio Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267 (Catalog # M00016-1). Tested in IHC, WB applications. This antibody reacts with Human. |
| Function: | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. |
| Cell localization: | Cytoplasm. Nucleus. |
| Clone: | Clone: RM267 |
| Isotype: | Rabbit IgG |
| Purification: | Protein A affinity purified from an animal origin-free culture supernatant |
| Storage conditions: | Store at -20°C for one year. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry (IHC): 1:500-1:1000 dilution WB: 1:500-1:1000 dilution. |