| Supplier: | Boster |
|---|---|
| Reference: | M00024-2 |
| Name: | Anti-Akt (E17K Mutant) AKT1 Rabbit Monoclonal Antibody, Clone#RM336 |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Monoclonal Antibodies |
| Research Area: | Apoptosis,Cancer,Cell Cycle,Cell Death,Epigenetics and Nuclear Signaling,Metabolism,Metabolism Processes,Nuclear,Pathways and Processes,Protein Phosphorylation,Ser/Thr Kinases,Serine/Threonine Kinases,Signal Transduction |
| Aditional Names: | RAC-alpha serine/threonine-protein kinase;2.7.11.1;Protein kinase B;PKB;Protein kinase B alpha;PKB alpha;Proto-oncogene c-Akt;RAC-PK-alpha;AKT1;PKB, RAC; |
| Unit: | 50ug |
| Concentration: | 1 mg/mL |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide corresponding to the Akt E17K Mutant |
| Host: | Rabbit |
| Reactivity: | Human |
| Cross Reactivity: | This antibody reacts to the Akt E17K mutant. No cross-reactivity with wild type Akt. |
| Application: | WB,ELISA,IHC |
| Description: | Boster Bio Anti-Akt (E17K Mutant) AKT1 Rabbit Monoclonal Antibody, Clone#RM336 (Catalog # M00024-2). Tested in WB, ELISA, IHC applications. This antibody reacts with Human. |
| Function: | AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine |
| Cell localization: | Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where |
| Clone: | Clone: RM336 |
| Isotype: | Rabbit IgG |
| Purification: | Protein A affinity purified from an animal origin-free culture supernatant |
| Storage conditions: | Store at -20°C for one year. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB: 0.1 ug/mL – 0.5 ug/mL ELISA: 0.05 ug/mL - 0.5 ug/mL Immunohistochemistry: 0.2 – 1 ug/mL. |