| Supplier: | Boster | |
|---|---|---|
| Reference: | A00526-2 | |
| Name: | Anti-ATG16L Antibody | |
| Category: | Antibody | |
| Subcategory: | Primary Antibodies | |
| Research Area: | Cancer,Cardiovascular,Cell Biology,Metabolism,Neuroscience,Autophagy | |
| Aditional Names: | Autophagy-related protein 16-1, APG16-like 1, ATG16L1, APG16L | |
| Unit: | 80ul 400ul | |
| Clonality: | Polyclonal | |
| Price: | Consultar | |
| Immunogen: | This ATG16L antibody is generated from rabbits immun | |
| Host: | Rabbit | |
| Reactivity: | Human, Mouse | |
| Application: | IF,WB,IHC-P | |
| Description: | Boster Bio Anti-ATG16L Antibody (Catalog # A00526-2). Tested in IF, WB, IHC-P application(s). This antibody reacts with Human, Mouse. | |
| Function: | Plays an essential role in both canonical and non-canonical autophagy: interacts with ATG12-ATG5 to mediate the lipidation to ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP) (PubMed:Cell localization: | Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Note=Recruited to omegasomes membranes by WIPI2 (By similarity). Omegasomes are e |
| Isotype: | Rabbit IgG | |
| Purification: | This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage conditions: | Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Assay inforation: | IF: 1:25 WB: 1:1000 IHC-P: 1:10-1:50 |