| Supplier: | Boster |
|---|---|
| Reference: | M00159-2 |
| Name: | Anti-CDK4 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Monoclonal Antibodies |
| Research Area: | Cancer,Cell Biology,T Cells |
| Aditional Names: | Cyclin-dependent kinase 4, Cell division protein kinase 4, PSK-J3, CDK4 |
| Unit: | 50ul 200ul |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Immunogen: | This CDK4 antibody is generated from a mouse immuniz |
| Host: | Mouse |
| Reactivity: | Human, Mouse |
| Application: | WB,IHC-P |
| Description: | Boster Bio Anti-CDK4 Antibody (Catalog # M00159-2). Tested in WB, IHC-P application(s). This antibody reacts with Human, Mouse. |
| Function: | Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the |
| Cell localization: | Cytoplasm. Nucleus. Nucleus membrane. Note=Cytoplasmic when non-complexed Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) t |
| Clone: | Clone: 1529CT850.162.73 |
| Isotype: | IgG2a,? |
| Purification: | This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage conditions: | Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Assay inforation: | IHC: 1:300 WB: 1:2000 IHC-P: 1:25 |