Trastuzumab - Research Grade Biosimilar

Supplier: ProSci
Reference: 21-854
Name: Trastuzumab - Research Grade Biosimilar
Category: Antibody
Subcategory: Primary Antibodies,Biosimilars
Research Area: Other
Aditional Names: NEU; NGL; HER2; TKR1; CD340; HER-2; VSCN2; MLN 19; c-ERB2; c-ERB-2; HER-2/neu
Unit: 0.1 mg
Concentration: batch dependent
Clonality: Recombinant
Conjugation: Unconjugated
Price: Consultar
Immunogen: Humanized / ERBB2 (HER2, Tyrosine kinase-type cell s
Isotype: Human IgG1
Purification: >95%
Storage conditions: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks). Store at -20 °C 12 months. Store at -80°C long term.
Note: Treatment of HER2-overexpressing breast cancer cell lines with Trastuzumab results in induction of p27KIP1 and the Rb-related protein, p130, which in turn significantly reduces the number of cells undergoing S-phase. A number of other phenotypic changes a