Supplier: | Boster |
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Reference: | M01819 |
Name: | Anti-FoxO4/Afx Rabbit Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
Research Area: | Domain Families,Epigenetics and Nuclear Signaling,Forkhead Box,Transcription |
Aditional Names: | Forkhead box protein O4;Fork head domain transcription factor AFX1;FOXO4;AFX, AFX1, MLLT7; |
Unit: | 30ul 100 ?l |
Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | A synthesized peptide derived from human FoxO4 |
Host: | Rabbit |
Reactivity: | Human |
Application: | IHC,WB |
Description: | Boster Bio Anti-FoxO4/Afx Rabbit Monoclonal Antibody catalog # M01819. Tested in IHC, WB applications. This antibody reacts with Human. |
Function: | Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activa |
Cell localization: | Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm. |
Clone: | Clone: HEI-6 |
Isotype: | Rabbit IgG |
Purification: | Affinity-chromatography |
Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | WB 1:5000-1:20000 IHC 1:50-1:200 |