| Supplier: | Boster |
|---|---|
| Reference: | M01819 |
| Name: | Anti-FoxO4/Afx Rabbit Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
| Research Area: | Domain Families,Epigenetics and Nuclear Signaling,Forkhead Box,Transcription |
| Aditional Names: | Forkhead box protein O4;Fork head domain transcription factor AFX1;FOXO4;AFX, AFX1, MLLT7; |
| Unit: | 30ul 100 ?l |
| Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A synthesized peptide derived from human FoxO4 |
| Host: | Rabbit |
| Reactivity: | Human |
| Application: | IHC,WB |
| Description: | Boster Bio Anti-FoxO4/Afx Rabbit Monoclonal Antibody catalog # M01819. Tested in IHC, WB applications. This antibody reacts with Human. |
| Function: | Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activa |
| Cell localization: | Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm. |
| Clone: | Clone: HEI-6 |
| Isotype: | Rabbit IgG |
| Purification: | Affinity-chromatography |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB 1:5000-1:20000 IHC 1:50-1:200 |