TOP1 DNA Topoisomerase-I 70kDa Recombinant Protein Human
Supplier:
Boster
Reference:
PROTP11387
Name:
TOP1 DNA Topoisomerase-I 70kDa Recombinant Protein Human
Category:
Protein
Subcategory:
Recombinant Proteins
Aditional Names:
DNA topoisomerase 1; EC 5.99.1.2; DNA topoisomerase I; TOP1; Scl-70
Unit:
5ug 20ug 1mg
Price:
Consultar
Application:
WB
Description:
Recombinant TOP1 70kDa protein is an enzyme fragment having a molecular mass of 72KDa (pH 9.4). TOP1 70kDa protein is fused to a hexa-histidine purification tag. Applications: Western blot with anti TOP1 70kDa autoantibody positive sample or monoclonal an
Function:
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site i
Cell localization:
Nucleus, nucleolus
Purification:
Greater than 95% as determined by SDS-PAGE.
Storage conditions:
Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
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