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TOP1 DNA Topoisomerase-I 70kDa Recombinant Protein Human

Supplier: Boster
Reference: PROTP11387
Name: TOP1 DNA Topoisomerase-I 70kDa Recombinant Protein Human
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: DNA topoisomerase 1; EC 5.99.1.2; DNA topoisomerase I; TOP1; Scl-70
Unit: 5ug 20ug 1mg
Price: Consultar
Application: WB
Description: Recombinant TOP1 70kDa protein is an enzyme fragment having a molecular mass of 72KDa (pH 9.4). TOP1 70kDa protein is fused to a hexa-histidine purification tag. Applications: Western blot with anti TOP1 70kDa autoantibody positive sample or monoclonal an
Function: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site i
Cell localization: Nucleus, nucleolus
Purification: Greater than 95% as determined by SDS-PAGE.
Storage conditions: Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
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