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Human FASL / CD95LG / CD95 Ligand ELISA Kit PicoKine®

Supplier: Boster
Reference: EK0337
Name: Human FASL / CD95LG / CD95 Ligand ELISA Kit PicoKine®
Category: ELISA kit
Subcategory: PicoKine® ELISA Kits
Research Area: Apoptosis,Caspases,Cell Biology,Cytokines,Hematopoietic Progenitors,Immunology,Innate Immunity,Intracellular,Lymphoid,Receptors,Stem Cells,T Lymphocytic Lineage,TNF Superfamily
Aditional Names: Tumor necrosis factor ligand superfamily member 6;Apoptosis antigen ligand;APTL;CD95 ligand;CD95-L;Fas antigen ligand;Fas ligand;FasL;CD178;Tumor necrosis factor ligand superfamily member 6, membrane form;Tumor necrosis factor ligand superfamily member 6, soluble form;Receptor-binding FasL ectodomain;Soluble Fas ligand;sFasL;ADAM10-processed FasL form;APL;FasL intracellular domain;FasL ICD;SPPL2A-processed FasL form;SPA;FASLG;APT1LG1, CD95L, FASL, TNFSF6;
Unit: 96 wells/kit, with removable strips.
Price: Consultar
Immunogen: Expression system for standard: CHO; Immunogen seque
Reactivity: Human
Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
Application: ELISA
Description: Human FASL / CD95LG / CD95 Ligand ELISA Kit PicoKine® (96 Tests). Quantitate Human FASLG in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 2pg/ml.
Function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:92
Cell localization: Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle lumen. Lysosome lumen. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination (PubMed:17164290). Colocalizes with the
Storage conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Assay inforation: Dilution ratio of 1:1, concentration in serum and plasma is 40-218 pg/ml.
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